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KMID : 0370920120290020073
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Yeungnam Univercity Journal of Medicine
2012 Volume.29 No. 2 p.73 ~ p.76
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Obesity and Insulin Resistance in Childhood
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Choi Kwang-Hae
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Abstract
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More and more children are becoming obese and overweight due to several factors that include a high energy density in the diet (a high fat intake) and low energy expenditure. Consequently childhood obesity is becoming a significant health problem. Fat tissue releases many cytokines such as resistin, tumor necrosis factor-α, leptin, interleukin-6. These adipocytokines induce obesity-related insulin resistance. Insulin resistance is a key component of obesity-related metabolic problems such as hypertension, type 2 diabetes mellitus, dyslipidemia, non-alcoholic steatohepatitis, acanthosis nigricans and polycystic ovarian syndrome. This review article focused on insulin resistance and its related metabolic diseases.
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KEYWORD
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Childhood obesity, Insulin resistance, hypertension, Non-alcoholic steatohepatitis, Polycystic ovarian syndrome
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